I've been trying to convert my media items into mp3 and it says "can' open file destination". I downloaded the lame enc64 that it said to and placed it in the user plugins folder it told me to. I even went into options and put it as a VST in there too but no luck. :( Someone help?

Are you sure that the destination is a valid path? Mac or pc, 32 or 64 bit Reaper?

Yep, i just have it routed to the source file. Is it saying it can't open the file from where it's saved? PC-64bit

Well, i am not sure...but "cant open file destination" sounds to me like it cant open the destination where it is supposed to save the mp3. And sorry if its me being a little slow, but you have what routed to which source?