I use DP 3.11 with a Mix Core and an Adat bridge. I don't do anything really heavy audio-wise in DP (I'm forced to use DP for composing work, otherwise I would stay in ProTools altogether.) I also use other rigs that are just DP and I work a lot with just PT. DP w/TDM works OK. I haven't come across any serious bugs. Mixing in DP just isn't as good as PT, with or without DAE, and editing audio is a pain. But the TDM plugins work, and it acts mostly like you would expect.

I started out with DP + PT, then to any all MOTU-based hardware system, then back to a DP + PT HD2 system under OSX Panther. It works great and I wholeheartedly recommend it.

As a former DP user - 2x through 3x, I certainly feel your pain. I now work 100% of the time in PT and there are a couple things I dearly miss, especially for film work. The tempo automation is the biggest for me. Yes you can work around in PT,and I often do, but it was so darn easy in DP. To answer you last post - Softsynths in PT - IMHO not abysmal at all. I use Atmosphere, Trilogy, Stylus, Lounge Lizard, Battery, B4, Reason, Live, SampleTank II, Virus, Synth One, Synth Spider, Pro53. With the exception of SampleTank II, all work great and with no problems on my G5/PT 6.2.3. SampleTank II is still a bit buggy - so I tend to print often and move on, which, frankly, forces me to work more efficiently and spend less time getting super anal on midi arrangements. Not sure what you mean by your second question - Yes you can combine native and TDM plugs in a TDM environment. You just can't use TDM plugs on a native only system. MIDI beat clock rocks in PT 6.2.3. I constantly use tempo based effects in my compositions. TL everyphase, and all of the sound toys plugs are awesome as tempo based plugs. MIDI timing is pretty good. Via rewire extremely solid. I do have to beat detective my battery drum parts once printed as there is usually some minor slop - but only in heavy dance music when ther are many percussive elements working together. All in all I'd say PT does about 80% of what I used to do in DP. I hear there is going to be a major MIDI overhaul in PT soon, so hopefully that will get me to 95% or 100% - we'll see... Hope this helps...

Boundalien, How do you like Synth One from McDSP. I own the Virus Indigo and was wondering if it complements it or is it about the same. I tried the demo about 1 year ago but I know it has been updated since. Thanks.

Dutchmuzic- I wasn't really crazy about S1 when I first got it about a year ago. But I got a demo from Colin at NAMM this year and the updates since it's release are really quite good. I don't think it really replaces Indigo - but it definitely has it's own sound and the ability to take samples/waveforms and really $#%^ them up in S1 makes for some cool sound design possibilities. Sometimes I'm just a bit bored w/ Indigo and this makes for a nice TDM option when creating a bass line or a lead... (when I'm not using Trilogy, which is my go to bass soft synth) Bottom line is it won't make you throw Indigo away, but it's worth the price to have another TDM synth option. My .02 for what its worth!!!